A Look at the Clinical Trial Data for Vardenafil 20 mg

Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability. -Maximum dose: 20 mg once a day Patients on stable alpha blocker therapy: -Initial dose: 5 mg orally once a day Comments: -Sexual stimulation is required for a response to treatment. -A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers. 65 years or older: -Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity Comments: Sexual stimulation is required for a response to treatment. Since Levitra is used as needed, you are not likely to be on a dosing schedule.

Key Participants Requirements

Stop using Levitra and call your doctor at once if you have: ringing in your ears, or sudden hearing loss; ringing in your ears, or sudden hearing loss; swelling in your hands, ankles, or feet; swelling in your hands, ankles, or feet; a light-headed feeling, like you might pass out; or a light-headed feeling, like you might pass out; or flushing (sudden warmth, redness, or tingly feeling); flushing (sudden warmth, redness, or tingly feeling); This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Do not use Levitra with similar medications such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). Tell your doctor about all other medications you use for erectile dysfunction.

A comprehensive review of erectile dysfunction in men with diabetes

This list is not complete and many Other drugs may interact with vardenafil. This includes mail order levitra online prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Levitra only for the for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

General Dose Information

Efficacy of patients with LEVITRA treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: LEVITRA treatment improved the patient's erectiondate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: LEVITRA improved the patient's erection after Minimum and Maximum Intervals between LEVITRA intake and the start of intercoursedate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Reporting a second successful intercourse within 24 hours of dosingdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Patients prefer LEVITRA over last Erectile Dysfunction treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Tolerability of patients with LEVITRA treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionYesSafety Issue: )]TJ /C2_0 1 Tf 0 Tc 0 Tw 7.98 0 0 7.98 49.405 366.8227 Tm <004A>Tj /TT1 1 Tf 12 0 0 12 52.705 361.3027 Tm ( )Tj /TT0 1 Tf 0.0001 Tc -0.0001 Tw 0.28 0 Td ( Flexible dose studies started all )Tj 0 Tc 0 Tw 13.055 0 Td [(patients at LEVITRA 10 m)7.8 (g)-5 ( and allo)]TJ -0.0002 Tc -0.0005 Tw 14.83 0 Td (wed decrease in dose to 5 mg or )Tj 0.0001 Tc -0.0001 Tw -27.66 -1.145 Td (increase in dose to 20 mg based on side effects and efficacy. )Tj 0 Tc -0.0006 Tw -0.78 -1.655 Td (Back pain was reported in 2.0% of patients treated)Tj 0 Tw ( with LEVITRA and 1.7% of patients on placebo. )Tj 0.0001 Tc -0.0026 Tw 0 -1.315 TD (Placebo-controlled trials suggested )Tj 0.0002 Tc -0.001 Tw 14.25 0 Td (a dose effect in the incidence of)Tj 0.0004 Tc -0.0016 Tw 12.71 0 Td [( som)8.2 (e)-0.8 ( adverse events \(headache, )]TJ -0.0003 Tw -26.96 -1.15 Td (flushing, dyspepsia, nausea, rhinitis\) over the )Tj 0.0001 Tc 0.0004 Tw 18.37 0 Td [(5 mg, 10 m)7.9 (g, and 20 m)7.9 (g doses of LEVITRA. The )]TJ 0.0008 Tc -0.0018 Tw -18.37 -1.15 Td [(f)3.8 (o)0.8 (llowing se)4.6 (ction identif)3.8 (i)-1.4 (es add)5.8 (ition)5.8 (a)4.6 (l, less f)3.8 (r)-1.2 (equ)5.8 (e)]TJ 0.001 Tc 19.99 0 Td [(nt events \(<)5 (2%\) repo)6 (rte)4.8 (d)1 ( during th)6 (e clin)6 (ical )]TJ 0.0006 Tc -0.002 Tw -19.99 -1.15 Td [(developm)8.4 (ent of LEVITRA. Excluded from)8.4 ( this list ar)]TJ -0.0027 Tw 21.44 0 Td [(e those events that are infrequ)5.6 (e)4.4 (nt and m)8.4 (i)-1.6 (nor, )]TJ 0.0003 Tc -0.0009 Tw -21.44 -1.145 Td [(those events that m)8.1 (a)-0.9 (y be commonly observed in the )]TJ 0.0001 Tc -0.0013 Tw (absence of drug therapy, a)Tj 0.0003 Tc -0.0015 Tw 31.49 0 Td (nd those events that are )Tj -0.0001 Tc 0.0001 Tw -31.49 -1.155 Td (not reasonably associated with the drug. Do not take Levitra more than once a day. Allow 24 hours to pass between doses. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Grapefruit and Seville oranges may interact with vardenafil and cause side effects.

• Levitra 20 mg Bayer is manufactured by Bayer Pharmaceuticals.
• It is often marketed under the brand name Levitra.
• The medication can be prescribed for men with erectile dysfunction.
• Levitra works by relaxing blood vessel muscles.
• It is available in tablet form for oral use.
• The recommended dose is usually 10-20 mg depending on need.
• Generics of Levitra 20 mg Bayer might be available in some markets.
• Patients should avoid heavy meals close to taking the medication.
• Common side effects may include nasal congestion and upset stomach.
• Levitra 20 mg Bayer may interact with certain blood pressure medicines.
• Always follow your doctor’s instructions when using Levitra.

Avoid consuming grapefruit products and orange marmalades. Drinking alcohol can increase certain side effects of Levitra.

Product	Dosage	Quantity + Bonus	Price
Levitra Original	20mg	34 + 2 Pills	188.51€ 179.53€	Buy
Levitra Original	20mg	64 + 4 Pills	298.45€ 284.24€	Buy
Levitra Generic	40mg	60 + 4 Pills	162.37€ 154.64€	Buy
Levitra Generic	20mg	360 + 10 Pills	458.44€ 436.61€	Buy
Levitra Professional	20mg	360 + 6 Pills	914.63€ 871.08€	Buy
Levitra Generic	20mg	10 Pills	31.49€ 29.99€	Buy
Levitra Generic	60mg	120 + 8 Pills	372.33€ 354.60€	Buy
Levitra Generic	40mg	270 + 10 Pills	561.89€ 535.13€	Buy
Levitra Generic	20mg	60 + 6 Pills	131.11€ 124.87€	Buy
Levitra Generic	60mg	20 Pills	81.30€ 77.43€	Buy
Levitra Professional	20mg	270 + 6 Pills	738.98€ 703.79€	Buy

Do not use any other medicine to treat impotence unless your doctor tells you to.

Trial summary

)Tj 0 Tc 0.0037 Tw 1.5 -1.315 Td (BODY AS A WHOLE: anaphylactic)Tj 0.0008 Tc -0.0015 Tw 14.775 0 Td [( reaction \(in)5.8 (cluding lary)5.8 (ngeal edem)8.6 (a\), asthen)5.8 (ia, f)8.8 (ace edem)8.6 (a, )]TJ 0.0009 Tc 0 Tw -14.775 -2.3 Td (pain )Tj 0.0004 Tc -0.0004 Tw 0 -2.805 TD [(AUDITOR)-2.6 (Y)2.6 (: tinnitus )]TJ -0.0003 Tc 0.0003 Tw 0 -1.31 TD [(CARDIOVASCULAR:)-7.5 ( angina pectoris, ches)]TJ 0.0003 Tc -0.0003 Tw 18.11 0 Td [(t pain, hypertension, hypotension, m)8.1 (yocardial )]TJ 0.0005 Tc -0.0005 Tw -18.11 -1.155 Td [(ischem)8.3 (ia, myocardial inf)8.5 (a)-0.7 (rction, palpitation, )]TJ -0.0001 Tc 0.0001 Tw 17.97 0 Td (postural hypotension, s)Tj 0 Tc 0 Tw 9.245 0 Td (yncope, tachycardia )Tj 0.0002 Tc -0.0002 Tw -27.215 -1.31 Td [(DIGESTIVE: abdom)8 (inal pain, abnorm)8 (al liver f)]TJ -0.0027 Tw 18.88 0 Td [(unction tests, diarrhea, dry )-7.5 (m)8 (outh, dysphagia, )]TJ 0.0005 Tc -0.003 Tw -18.88 -1.155 Td [(esophagitis, gastritis, gas)4.7 (t)-1.7 (roesophag)5.5 (e)]TJ 0.0006 Tc -0.0006 Tw 14.83 0 Td [(al reflux, G)7.8 (G)2.8 (TP increas)4.8 (ed, vom)8.4 (iting )]TJ 0.0004 Tc -0.0004 Tw -14.83 -1.32 Td (MUSCULOSKELETAL: arthra)Tj 0.0005 Tc -0.0025 Tw 12.805 0 Td (lgia, back pain, myalgia, neck pain )Tj 0.0001 Tc -0.0017 Tw -12.805 -1.315 Td [(NERVOUS:)-7.1 ( hypertonia, hypesthesia, insom)7.9 (nia)]TJ 0.0002 Tc 18.855 0 Td [(, paresthesia, som)8 (nolence, vertigo )]TJ 0.0004 Tc -0.0004 Tw -18.855 -1.315 Td (RESPIRATORY: dyspnea, ep)Tj -0.0003 Tc 0.0003 Tw 12.09 0 Td (istaxis, pharyngitis )Tj 0 Tc 0.0016 Tw -12.09 -1.32 Td (SKIN AND APPENDAGES: photosensitivity)Tj 0.0002 Tc -0.0014 Tw 18.42 0 Td ( reaction, pruritus, rash, sweating )Tj ET q 1 0 0 1 -8.195038 -34.037292 cm /CS0 CS 0.004 0.004 0.004 SCN 0.75 w 1 j 1 J q 1 0 0 1 61.2 652.08 cm 0 0 m 432 0 l 0.48 -22.68 m 432.48 -22.68 l 0.48 -60.3 m 432.48 -60.3 l 0 -203.7 m 432 -203.7 l S Q Q /Artifact <>BDC Q q 1 0 0 1 120.6970062 785.2004395 cm /GS1 gs /Fm0 Do Q EMC /Artifact <>BDC q 1 0 0 1 612 773.2004395 cm /GS1 gs /Fm1 Do Q EMC endstream endobj 201 0 obj <>>>/Resources 234 0 R/Subtype/Form>>stream 0 g 0 G 0 i 0 J []0 d 0 j 1 w 10 M 0 Tc 0 Tw 100 Tz 0 TL 0 Tr 0 Ts BT /ArialRoundedMTBold 10 Tf 0 0 1 rg 65.791 -7.9 Td (This ) Tj 22.92 0 Td (label ) Tj 26.055 0 Td (may ) Tj 22.71 0 Td (not ) Tj 18.12 0 Td (be ) Tj 14.692 0 Td (the ) Tj 18.023 0 Td (latest ) Tj 29.595 0 Td (approved ) Tj 48.974 0 Td (by ) Tj 14.17 0 Td (FDA. ) Tj -281.05 -12 Td (For ) Tj 18.96 0 Td (current ) Tj 38.765 0 Td (labeling ) Tj 41.055 0 Td (information, ) Tj 61.25 0 Td (please ) Tj 34.707 0 Td (visit ) Tj 22.299 0 Td ( Tj ET endstream endobj 202 0 obj <>>>/Resources 236 0 R/Subtype/Form>>stream 0 g 0 G 0 i 0 J []0 d 0 j 1 w 10 M 0 Tc 0 Tw 100 Tz 0 TL 0 Tr 0 Ts BT /ArialRoundedMTBold 10 Tf 0 0 1 rg 0 -7.9 Td ( ) Tj ET endstream endobj 236 0 obj <> endobj 237 0 obj <> endobj 235 0 obj <>stream �5H�8CTzd#E���[��w���ᮆ�)ȼ�7�)��ࢠ1�97���8�������{�s ��~�N�4T$�C#A�}�A�_��r�y���XXm�d�=��jc����}�jˇX���(��? Proportion of vardenafil subjects with a 50% or greater decrease from baseline in mean sperm concentration at 6 months (LOCF), compared to placebo after repeated usedate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Mean sperm concentrationdate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Mean sperm countdate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Proportion of sildenafil subjects with a 50% or greater decrease from baseline in mean sperm concentration at 6 months (LOCF), compared to placebo and vardenafil after repeated usedate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Washington, DC - The FDA gave approval yesterday to vardenafil (Levitra®, Bayer and Glaxo Smith Kline), an oral erectile-dysfunction drug that works through the same mechanism as sildenafil (Viagra®, Pfizer). Like sildenafil, vardenafil can seriously affect blood pressure and should not be taken by those on alpha blockers or nitrates. The recommended dose is 10 mg taken one hour before sexual activity, with 20-, 5.0-, and 2.5-mg doses available.

Professional resources

Vardenafil is a phosphodiesterase inhibitor and, like sildenafil, is strongly contraindicated if patients are taking nitrates (nitroglycerin tablets or patches) or alpha blockers, due to the possibility of a steep drop in blood pressure.

Bayer Savings Card

Get emergency medical help if you have signs of an allergic reaction to Levitra: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Levitra and get emergency medical help if you have: heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; vision changes or sudden vision loss; or vision changes or sudden vision loss; or erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis). erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis). Stop using Levitra and call your doctor at once if you have: ringing in your ears, or sudden hearing loss; ringing in your ears, or sudden hearing loss; swelling in your hands, ankles, or feet; swelling in your hands, ankles, or feet; a light-headed feeling, like you might pass out; or a light-headed feeling, like you might pass out; or flushing (sudden warmth, redness, or tingly feeling); flushing (sudden warmth, redness, or tingly feeling); This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Where to participate

Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability. -Maximum dose: 20 mg once a day Patients on stable alpha blocker therapy: -Initial dose: 5 mg orally once a day Comments: -Sexual stimulation is required for a response to treatment. -A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers. 65 years or older: -Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity Comments: Sexual stimulation is required for a response to treatment. Since Levitra is used as needed, you are not likely to be on a dosing schedule.

Achieving treatment optimization with sildenafil citrate (Viagra(R)) in patients with erectile dysfunction

Do not take Levitra more than once a day. Allow 24 hours to pass between doses. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Grapefruit and Seville oranges may interact with vardenafil and cause side effects. Avoid consuming grapefruit products and orange marmalades.

Phosphodiesterase Type 5 Inhibitors: The Day After

Drinking alcohol can increase certain side effects of Levitra. Do not use any other medicine to treat impotence unless your doctor tells you to. Get emergency medical help if you have signs of an allergic reaction to Levitra: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Levitra and get emergency medical help if you have: heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; vision changes or sudden vision loss; or vision changes or sudden vision loss; or erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis). erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis). You may report side effects to FDA at 1-800-FDA-1088. Do not use Levitra with similar medications such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). Tell your doctor about all other medications you use for erectile dysfunction. This list is not complete and many Other drugs may interact with vardenafil.

Condition	Warning
Use of Nitrates	Contraindicated due to risk of severe hypotension
Severe Cardiovascular Conditions	Seek medical advice before use
Liver or Kidney impairment	Dose adjustment may be required
Hypersensitivity to Vardenafil	Avoid use

This includes mail order levitra online prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

• Levitra 20 mg Bayer is designed for adult men with ED.
• It should be used with caution in patients with liver or kidney issues.
• The medication may cause visual disturbances in some users.
• Levitra 20 mg Bayer does not protect against sexually transmitted infections.
• Measuring your response can help determine proper dosage.
• Avoid taking Levitra if you have any known allergies to it.
• Some users report improved confidence after taking Levitra.
• The drug can sometimes cause a mild decrease in blood pressure.
• You should not crush or chew the tablets; swallow whole.
• Use medication only as prescribed by a healthcare professional.
• Levitra 20 mg Bayer is part of a broader class of ED treatments.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Levitra only for the for the indication prescribed.

• Levitra 20 mg Bayer can be part of a comprehensive ED management plan.
• Regular check-ups are recommended for users on this medication.
• Discontinue use and seek medical advice if adverse reactions occur.
• Levitra may be ineffective if taken with high-fat meals.
• Use with caution if you have any bleeding or clotting disorders.
• The medication may interact with certain antifungal and antibiotic drugs.
• Patients should inform their doctor about all current medications.
• Timing of medication can influence the success of treatment.
• Levitra 20 mg Bayer does not cause addiction or dependency.
• The drug is often preferred for its rapid onset of action.
• It’s important to have realistic expectations about the results.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More Relevant Posts

Efficacy of patients with LEVITRA treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: LEVITRA treatment improved the patient's erectiondate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: LEVITRA improved the patient's erection after Minimum and Maximum Intervals between LEVITRA intake and the start of intercoursedate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Reporting a second successful intercourse within 24 hours of dosingdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Patients prefer LEVITRA over last Erectile Dysfunction treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionNoSafety Issue: Tolerability of patients with LEVITRA treatmentdate_rangeTime Frame:After 6 monthsenhanced_encryptionYesSafety Issue: )]TJ /C2_0 1 Tf 0 Tc 0 Tw 7.98 0 0 7.98 49.405 366.8227 Tm <004A>Tj /TT1 1 Tf 12 0 0 12 52.705 361.3027 Tm ( )Tj /TT0 1 Tf 0.0001 Tc -0.0001 Tw 0.28 0 Td ( Flexible dose studies started all )Tj 0 Tc 0 Tw 13.055 0 Td [(patients at LEVITRA 10 m)7.8 (g)-5 ( and allo)]TJ -0.0002 Tc -0.0005 Tw 14.83 0 Td (wed decrease in dose to 5 mg or )Tj 0.0001 Tc -0.0001 Tw -27.66 -1.145 Td (increase in dose to 20 mg based on side effects and efficacy. )Tj 0 Tc -0.0006 Tw -0.78 -1.655 Td (Back pain was reported in 2.0% of patients treated)Tj 0 Tw ( with LEVITRA and 1.7% of patients on placebo. )Tj 0.0001 Tc -0.0026 Tw 0 -1.315 TD (Placebo-controlled trials suggested )Tj 0.0002 Tc -0.001 Tw 14.25 0 Td (a dose effect in the incidence of)Tj 0.0004 Tc -0.0016 Tw 12.71 0 Td [( som)8.2 (e)-0.8 ( adverse events \(headache, )]TJ -0.0003 Tw -26.96 -1.15 Td (flushing, dyspepsia, nausea, rhinitis\) over the )Tj 0.0001 Tc 0.0004 Tw 18.37 0 Td [(5 mg, 10 m)7.9 (g, and 20 m)7.9 (g doses of LEVITRA.

• Levitra 20 mg Bayer is supplied in blister packs for convenience.
• It is essential to adhere to prescribed timing and dosage.
• OTC availability varies by country; prescription is generally required.
• Patients should report any unusual eye or vision changes promptly.
• Levitra’s effects can be influenced by other health conditions.
• Men should avoid unnecessary driving or dangerous activities after use.
• The medication is part of a balanced approach to sexual health.
• Levitra may require dose adjustments based on individual response.
• Avoid using other ED medications simultaneously without medical advice.
• Nutritional supplements claiming to enhance ED are not regulated.
• Proper storage and handling ensure medication effectiveness.

The )]TJ 0.0008 Tc -0.0018 Tw -18.37 -1.15 Td [(f)3.8 (o)0.8 (llowing se)4.6 (ction identif)3.8 (i)-1.4 (es add)5.8 (ition)5.8 (a)4.6 (l, less f)3.8 (r)-1.2 (equ)5.8 (e)]TJ 0.001 Tc 19.99 0 Td [(nt events \(<)5 (2%\) repo)6 (rte)4.8 (d)1 ( during th)6 (e clin)6 (ical )]TJ 0.0006 Tc -0.002 Tw -19.99 -1.15 Td [(developm)8.4 (ent of LEVITRA. Excluded from)8.4 ( this list ar)]TJ -0.0027 Tw 21.44 0 Td [(e those events that are infrequ)5.6 (e)4.4 (nt and m)8.4 (i)-1.6 (nor, )]TJ 0.0003 Tc -0.0009 Tw -21.44 -1.145 Td [(those events that m)8.1 (a)-0.9 (y be commonly observed in the )]TJ 0.0001 Tc -0.0013 Tw (absence of drug therapy, a)Tj 0.0003 Tc -0.0015 Tw 31.49 0 Td (nd those events that are )Tj -0.0001 Tc 0.0001 Tw -31.49 -1.155 Td (not reasonably associated with the drug. )Tj 0 Tc 0.0037 Tw 1.5 -1.315 Td (BODY AS A WHOLE: anaphylactic)Tj 0.0008 Tc -0.0015 Tw 14.775 0 Td [( reaction \(in)5.8 (cluding lary)5.8 (ngeal edem)8.6 (a\), asthen)5.8 (ia, f)8.8 (ace edem)8.6 (a, )]TJ 0.0009 Tc 0 Tw -14.775 -2.3 Td (pain )Tj 0.0004 Tc -0.0004 Tw 0 -2.805 TD [(AUDITOR)-2.6 (Y)2.6 (: tinnitus )]TJ -0.0003 Tc 0.0003 Tw 0 -1.31 TD [(CARDIOVASCULAR:)-7.5 ( angina pectoris, ches)]TJ 0.0003 Tc -0.0003 Tw 18.11 0 Td [(t pain, hypertension, hypotension, m)8.1 (yocardial )]TJ 0.0005 Tc -0.0005 Tw -18.11 -1.155 Td [(ischem)8.3 (ia, myocardial inf)8.5 (a)-0.7 (rction, palpitation, )]TJ -0.0001 Tc 0.0001 Tw 17.97 0 Td (postural hypotension, s)Tj 0 Tc 0 Tw 9.245 0 Td (yncope, tachycardia )Tj 0.0002 Tc -0.0002 Tw -27.215 -1.31 Td [(DIGESTIVE: abdom)8 (inal pain, abnorm)8 (al liver f)]TJ -0.0027 Tw 18.88 0 Td [(unction tests, diarrhea, dry )-7.5 (m)8 (outh, dysphagia, )]TJ 0.0005 Tc -0.003 Tw -18.88 -1.155 Td [(esophagitis, gastritis, gas)4.7 (t)-1.7 (roesophag)5.5 (e)]TJ 0.0006 Tc -0.0006 Tw 14.83 0 Td [(al reflux, G)7.8 (G)2.8 (TP increas)4.8 (ed, vom)8.4 (iting )]TJ 0.0004 Tc -0.0004 Tw -14.83 -1.32 Td (MUSCULOSKELETAL: arthra)Tj 0.0005 Tc -0.0025 Tw 12.805 0 Td (lgia, back pain, myalgia, neck pain )Tj 0.0001 Tc -0.0017 Tw -12.805 -1.315 Td [(NERVOUS:)-7.1 ( hypertonia, hypesthesia, insom)7.9 (nia)]TJ 0.0002 Tc 18.855 0 Td [(, paresthesia, som)8 (nolence, vertigo )]TJ 0.0004 Tc -0.0004 Tw -18.855 -1.315 Td (RESPIRATORY: dyspnea, ep)Tj -0.0003 Tc 0.0003 Tw 12.09 0 Td (istaxis, pharyngitis )Tj 0 Tc 0.0016 Tw -12.09 -1.32 Td (SKIN AND APPENDAGES: photosensitivity)Tj 0.0002 Tc -0.0014 Tw 18.42 0 Td ( reaction, pruritus, rash, sweating )Tj ET q 1 0 0 1 -8.195038 -34.037292 cm /CS0 CS 0.004 0.004 0.004 SCN 0.75 w 1 j 1 J q 1 0 0 1 61.2 652.08 cm 0 0 m 432 0 l 0.48 -22.68 m 432.48 -22.68 l 0.48 -60.3 m 432.48 -60.3 l 0 -203.7 m 432 -203.7 l S Q Q /Artifact <>BDC Q q 1 0 0 1 120.6970062 785.2004395 cm /GS1 gs /Fm0 Do Q EMC /Artifact <>BDC q 1 0 0 1 612 773.2004395 cm /GS1 gs /Fm1 Do Q EMC endstream endobj 201 0 obj <>>>/Resources 234 0 R/Subtype/Form>>stream 0 g 0 G 0 i 0 J []0 d 0 j 1 w 10 M 0 Tc 0 Tw 100 Tz 0 TL 0 Tr 0 Ts BT /ArialRoundedMTBold 10 Tf 0 0 1 rg 65.791 -7.9 Td (This ) Tj 22.92 0 Td (label ) Tj 26.055 0 Td (may ) Tj 22.71 0 Td (not ) Tj 18.12 0 Td (be ) Tj 14.692 0 Td (the ) Tj 18.023 0 Td (latest ) Tj 29.595 0 Td (approved ) Tj 48.974 0 Td (by ) Tj 14.17 0 Td (FDA. ) Tj -281.05 -12 Td (For ) Tj 18.96 0 Td (current ) Tj 38.765 0 Td (labeling ) Tj 41.055 0 Td (information, ) Tj 61.25 0 Td (please ) Tj 34.707 0 Td (visit ) Tj 22.299 0 Td ( Tj ET endstream endobj 202 0 obj <>>>/Resources 236 0 R/Subtype/Form>>stream 0 g 0 G 0 i 0 J []0 d 0 j 1 w 10 M 0 Tc 0 Tw 100 Tz 0 TL 0 Tr 0 Ts BT /ArialRoundedMTBold 10 Tf 0 0 1 rg 0 -7.9 Td ( ) Tj ET endstream endobj 236 0 obj <> endobj 237 0 obj <> endobj 235 0 obj <>stream �5H�8CTzd#E���[��w���ᮆ�)ȼ�7�)��ࢠ1�97���8�������{�s ��~�N�4T$�C#A�}�A�_��r�y���XXm�d�=��jc����}�jˇX���(��? Proportion of vardenafil subjects with a 50% or greater decrease from baseline in mean sperm concentration at 6 months (LOCF), compared to placebo after repeated usedate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Mean sperm concentrationdate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Mean sperm countdate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Proportion of sildenafil subjects with a 50% or greater decrease from baseline in mean sperm concentration at 6 months (LOCF), compared to placebo and vardenafil after repeated usedate_rangeTime Frame:24 weeksenhanced_encryptionyesSafety Issue: Washington, DC - The FDA gave approval yesterday to vardenafil (Levitra®, Bayer and Glaxo Smith Kline), an oral erectile-dysfunction drug that works through the same mechanism as sildenafil (Viagra®, Pfizer). Like sildenafil, vardenafil can seriously affect blood pressure and should not be taken by those on alpha blockers or nitrates.

Ingredient	Quantity per tablet	Function
Vardenafil	20 mg	Active PDE5 inhibitor
Microcrystalline cellulose	-	Binder and filler
Lactose	-	Filler
Magnesium stearate	-	Lubricant
Hydroxypropyl methylcellulose	-	Coating agent
Titanium dioxide	-	White pigment for coating

The recommended dose is 10 mg taken one hour before sexual activity, with 20-, 5.0-, and 2.5-mg doses available.

Storage Condition	Details
Temperature	Store below 30°C (86°F)
Light Protection	Keep in a dry, opaque container
Humidity	Avoid moisture exposure
Out of reach of children	Yes

Vardenafil is a phosphodiesterase inhibitor and, like sildenafil, is strongly contraindicated if patients are taking nitrates (nitroglycerin tablets or patches) or alpha blockers, due to the possibility of a steep drop in blood pressure.